|
AMITRIPTYLINE HYDROCHLORIDE |
| Product Name |
: |
Amitriptyline Hydrochloride BP/EP/USP |
| Chemical Name |
: |
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N dimethyl-,hydrochloride |
| CAS Number |
: |
549-18-8 |
| Chemical Formula |
: |
C20H23N.HCl |
| Molecular Mass |
: |
313.86 g/mol |
| Therapeutic Category |
: |
Antidepressant |
| Test |
Specification |
| Description |
white or practically white, odorless or practically odorless, crystalline powder or small crystals |
| Identification |
BY IR BY UV Test for Chloride |
| Solubility |
Freely soluble in water, in alcohol and in Chloroform, and in methanol, insoluble in ether. |
| Heavy Metals |
Not more than 0.001% |
| Ph (1% Solution) |
Between 5.0 and 6.0 |
| Loss On Drying |
Not more than 0.5% |
| Assay on dried basis by HPLC |
Between 99 % w/w to 100.5 % w/w |
| Related Substances by TLC |
Any secondary spot : NMT 0.5%
Sum of all secondary spots : NMT 1.0% |
| Melting Range |
Between 195.0°C to 199.0°C |
|
|
